The assessment of chemical mixtures is a complex topic for toxicologists regulators and the public in this article the linkage between the science of toxicology and the needs of governmental regulatory agencies in the united states is explored through an overview of environmental regulations . A key factor in risk assessments of chemical mixtures is the availability of reliable data on the identity levels of exposure toxicokinetics toxicodynamics and toxicological interactions for the whole mixture or its individual components. Toxicology of chemical mixtures a review of mixtures assessment document for toxicology of chemical mixtures a review of mixtures assessment is available in various format such as pdf doc and epub which. Hence if the chemical potency of chemical a and b in a binary mixture was based on the effect concentration ec of each chemical causing x effect on any endpoint in a test system 1 ec xa and 1 ec xb then the sum of the concentration of chemicals c a and c b multiplied with their respective potency in a mixture provoking x effect would . Abstract assessment information while exposure to environmental hazards most often occurs with complex chemical mixtures the majority of existing toxicity data is for single compounds or simple mixtures thus presenting problems to the risk assessor
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